Covid-19 Information: Stay Updates – The New York Instances

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Johnson & Johnson has paused the massive late-stage medical trial of its coronavirus vaccine due to an “unexplained illness” in one of many volunteers, the corporate mentioned on Monday.

The corporate didn’t say whether or not the sick participant had acquired the experimental vaccine or a placebo. The pause was first reported by the well being information web site Stat.

Johnson & Johnson, which simply started the so-called Phase 3 trial of its vaccine final month, was behind a number of of its opponents within the vaccine race, however its vaccine had some benefits over others. It doesn’t have to be frozen, and it may need only one dose as an alternative of two. It will even be the most important trial, with a aim of enrolling 60,000 volunteers.

“Antagonistic occasions — diseases, accidents, and many others. — even these which can be severe, are an anticipated a part of any medical examine, particularly giant research,” the corporate mentioned in a statement. “We’re additionally studying extra about this participant’s sickness, and it’s necessary to have all of the information earlier than we share extra data.”

Trial pauses are sometimes lifted rapidly after the sickness is investigated and deemed to not be a severe security danger.

“It’s truly factor that these corporations are pausing these trials when these items come up,” mentioned Dr. Phyllis Tien, an infectious illness doctor on the College of California, San Francisco, a trial website for Johnson & Johnson and AstraZeneca. “We simply have to let the sponsor and the security board do their evaluate and tell us their findings.”

“It doesn’t imply that the opposed occasion is expounded to the vaccine, however it must be investigated completely,” mentioned Dr. Luciana Borio, who oversaw public well being preparedness for the Nationwide Safety Council beneath President Trump and was performing chief scientist on the Meals and Drug Administration beneath former President Barack Obama. Relying on the findings, she mentioned, extra knowledge could also be collected, trial guidelines could also be modified, or different steps could also be taken to make sure security.

Johnson & Johnson’s shouldn’t be the primary trial to be paused due to security issues. Two contributors in AstraZeneca’s trial became seriously ill after getting its vaccine. That trial was halted twice — most lately final month — and has nonetheless not resumed in america, although areas overseas swiftly broke the pause.

Each Johnson & Johnson and AstraZeneca developed their vaccines utilizing adenovirus vectors, modified viruses engineered to hold coronavirus genes into human cells. AstraZeneca’s vaccine used an adenovirus that causes widespread colds in chimpanzees. Johnson & Johnson’s used one other adenovirus, referred to as Ad26, which has additionally been utilized in its accepted vaccine for Ebola.

Consultants say questions of safety should be investigated and are one motive late-stage trials can’t be rushed — even for a president who has repeatedly claimed {that a} vaccine can be prepared earlier than the U.S. election on Nov. 3. “This sort of occasion epitomizes why vaccine improvement can’t be influenced by synthetic timelines corresponding to an election,” mentioned John Moore, a virologist at Weill Cornell Drugs.

Credit score…Vincenzo Pinto/Agence France-Presse — Getty Photographs

America could also be inside months of a profound turning level within the nation’s battle in opposition to the coronavirus: the primary working vaccine.

Demonstrating {that a} new vaccine is protected and efficient in lower than a 12 months would shatter the document for pace, the results of seven-day workweeks for scientists and billions of {dollars} of funding by the federal government.

The trail has not been with out bumps. Johnson & Johnson introduced Monday evening that it was halting its Section 3 trial after a volunteer obtained sick. And AstraZeneca additionally paused its trial, final month, after two contributors grew to become unwell.

Nonetheless, it’s tempting to take a look at the primary vaccine as President Trump does: an on-off change that can convey again life as we all know it. “As quickly because it’s given the go-ahead, we are going to get it out, defeat the virus,” he mentioned at a September news conference.

As a substitute, vaccine consultants say, we must always put together for a perplexing, irritating 12 months.

The primary vaccines could present solely average safety, low sufficient to make it prudent to maintain carrying a masks. By subsequent spring or summer season, there could also be a number of of those so-so vaccines.

Due to this array of choices, makers of a superior vaccine in early levels of improvement could battle to complete medical testing. And a few vaccines could also be abruptly withdrawn from the market as a result of they prove to not be protected.

“It has not but dawned on hardly anyone the quantity of complexity and chaos and confusion that can occur in a number of brief months,” mentioned Dr. Gregory Poland, the director of the Vaccine Analysis Group on the Mayo Clinic.

Credit score…Doug Mills/The New York Instances

President Trump, desperate to show he’s wholesome and energetic regardless of his recent hospitalization for Covid-19, returned to the campaign trail on Monday night in Florida, telling supporters he was absolutely recovered and subsequently resistant to the coronavirus — a declare for which there isn’t a conclusive scientific backing.

Onstage at a hangar on the Orlando Sanford Worldwide Airport, Mr. Trump mentioned he felt “so highly effective” and supplied to wade into the gang.

“I’ll kiss everybody in that viewers,” he mentioned. “I’ll kiss the fellows and the gorgeous ladies. Simply offer you an enormous fats kiss.”

The president spoke for about an hour. Many supporters within the crowd didn’t put on masks, together with a few of these chosen to face behind the president’s lectern and throughout the digital camera shot.

Mr. Trump claimed that vaccines in opposition to the virus “are going to be distributed very shortly,” though the Meals and Drug Administration has not but accepted one. The president additionally implied with out proof that the company was intentionally holding again on vaccine approvals to harm his probabilities of re-election. Learn a fact check of Mr. Trump’s claims on Monday here.

“Frankly, it’s an enormous political deal happening the place they don’t need it to be earlier than the election,” the president mentioned.

Mr. Trump, whose response to a pandemic that has killed greater than 214,000 People stays the most important menace to his re-election, additionally claimed with out proof that his Democratic rival, former Vice President Joseph R. Biden Jr., would delay the vaccine and “extend the pandemic.”

Mr. Trump’s arrival in Florida passed off solely hours after the White Home doctor, Dr. Sean P. Conley, mentioned the president had examined adverse “on consecutive days” utilizing a speedy coronavirus take a look at not meant for that objective.

Consultants cautioned that the take a look at’s accuracy has not yet been investigated enough to make sure that the president is virus-free or, as his physician claimed, “not infectious to others.”

With three weeks left within the race, Mr. Trump is running behind Mr. Biden. His polling numbers with seniors, a vital constituency that has been disproportionately harmed by the coronavirus, have been flagging.

Hours earlier than Monday’s rally, the nation’s high infectious illness knowledgeable, Dr. Anthony S. Fauci, warned that holding giant rallies was “asking for bother” with instances of the virus surging in lots of states.

Dr. Fauci, in an interview with CNN, mentioned that People wanted to be extra cautious within the fall and winter months, and warned that rising charges of infections in quite a few states urged People ought to be “doubling down” on precautions fairly than casting them apart.

United States › On Oct. 12 14-day
New cases 45,929 +19%
New deaths 351 –5%

Where cases are
per capita

Credit…Doug Mills/The New York Times

Major news organizations have become increasingly wary of sending journalists to travel with President Trump to White Home occasions and marketing campaign rallies, because the president and his aides proceed to shun security protocols after an outbreak of the virus inside their ranks.

The New York Instances, The Wall Road Journal and The Washington Publish are among the many main shops which have declined to assign reporters to journey with Mr. Trump as he returns to the path this week, saying they don’t have assurance that primary precautions can be taken to guard reporters’ well being.

Foremost among the many flouters is Mr. Trump himself, who, regardless of lately contracting the virus and spending three nights within the hospital, has proven little willingness to alter his habits: On Saturday, he said the virus would soon “disappear,” and on the best way to a rally in Florida on Monday, he boarded Air Power One — the place reporters have been seated within the cabin — with out carrying a masks.

A minimum of three White Home correspondents have examined optimistic for the coronavirus up to now two weeks, together with a Instances reporter who had traveled on Air Power One, Michael D. Shear.

Security issues can also complicate Mr. Trump’s tentative NBC city corridor on Thursday. NBC executives have requested the White Home for proof that their staff is not going to face undue dangers on the occasion, based on two individuals acquainted with discussions.

Among the many issues raised by reporters: Many flight attendants and Secret Service brokers on Air Power One haven’t worn masks; White Home aides who examined optimistic for the coronavirus, or have been probably uncovered, are returning to work earlier than the top of a two-week quarantine; and the marketing campaign has instituted few restrictions on the raucous rallies that Mr. Trump is now pledging to carry.

The White Home press secretary, Kayleigh McEnany — who briefed reporters final weekend with out carrying a masks, shortly earlier than she examined optimistic for the virus — mentioned on Monday that the Trump marketing campaign would distribute masks however wouldn’t require attendees to put on them.

Credit score…Petr David Josek/Related Press

The Czech Republic, now battling the very best charge of coronavirus an infection in Europe, will shut faculties Wednesday, becoming a member of Slovakia as the primary international locations on the Continent to impose sweeping faculty closures in an effort to curb the unfold of the virus.

“We solely have one shot at this, and it must be profitable to ensure that our nation overcomes the pandemic this time as nicely,” Prime Minister Andrej Babis instructed the nation Monday evening.

The college closures are an growth of measures that had already been put in place final month because the variety of instances began to develop in August earlier than exploding in September.

On Monday, all theaters, cinemas and zoos have been closed for at the very least two weeks. Eating places and bars have to shut at 8 p.m., and a most 4 individuals can be allowed per desk.

Even earlier than the official determination to shut faculties, dozens have been pressured to droop courses after academics and college students fell unwell.

The well being minister, Roman Prymula, an epidemiologist who was appointed final month to direct the battle in opposition to the virus, mentioned that the nation’s well being care system might quickly be overwhelmed, forcing the nation to take the painful step of closing faculties.

“We’ve got to do it, as a result of we shouldn’t have one other likelihood, we’re pressured to take such a measure that can inside two to a few weeks reverse the development, as a result of in any other case we are going to exhaust the hospital capability,” he mentioned.

As of Friday, the nation recorded 451.2 coronavirus instances per 100,000 inhabitants over a 14-day interval, based on statistics from European Middle for Illness Management and Prevention. The demise toll reached 1,045 on Monday, with greater than half the deaths — 618 — coming since September, based on the well being ministry.

The Czech Republic’s neighbor Slovakia is now frequently reporting over 1,000 new instances per day and introduced the closure of excessive faculties on Monday. Most universities had already moved on-line.

Prime Minister Igor Matovic referred to as the event “a severe second for Slovakia.”

The nation is contemplating limiting journey to its neighbor, which might be a rare improvement for the 2 international locations, which till 1993 fashioned one nation, Czechoslovakia.

Credit score…Mary Altaffer/Related Press

When the coronavirus pandemic closed workplaces round america in March, many corporations instructed their staff that it will be a brief hiatus.

Staff, they mentioned, can be again in cubicles inside a matter of weeks. Weeks become September. Then September become January. And now, with the virus still surging in some parts of the country, a rising variety of employers are delaying return-to-office dates once again, to the summer of 2021.

Google was one of many first to announce that July 2021 was its return date. Uber, Slack and Airbnb quickly adopted. Previously week, Microsoft, Goal, Ford Motor and The New York Instances mentioned they, too, had postponed the return of in-person work to subsequent summer season and acknowledged the inevitable: The pandemic isn’t going away anytime quickly.

Many extra corporations are anticipated to delay their return-to-office dates to maintain staff protected. And staff mentioned they have been in no rush to return, with 73 p.c of U.S. staff fearing that being of their office might pose a danger to their private well being and security, based on a study by Wakefield Analysis commissioned by Envoy, a office know-how firm.

Extra corporations are additionally saying that they are going to institute everlasting work-from-home insurance policies.

In Could, Facebook was one of the first to announce that it will enable many staff to work remotely even after the pandemic. Twitter, Coinbase, Shopify and Microsoft have additionally mentioned they might accomplish that.

The postponement of return dates is a “psychological blow for individuals who anticipated this to be a transition section,” mentioned Tsedal Neeley, a Harvard Enterprise Faculty professor who research distant work. “The truth is hitting that, ‘There gained’t be a vaccine as I anticipated in a short time. That is going to be my life, and I’d higher discover ways to do that.’”

Credit score…Bara Kristinsdottir for The New York Instances

Tourism is present process a downturn all around the world, however a number of components make Iceland significantly susceptible to the business’s crash: geographic isolation, a small home inhabitants, strict border measures and an financial system that — after a rare, decade-long tourism growth — had come to rely closely on overseas vacationers. A recent surge in coronavirus instances has added to Iceland’s challenges.

However whereas customer numbers are low, Iceland is positioning itself for a major tourism rebound after the pandemic. The federal government is investing greater than $12 million in tourism infrastructure, whereas bettering roads and harbors throughout the nation.

To maintain the tourism business afloat within the brief time period, the federal government can be investing greater than $9 million in a program that distributes free journey vouchers to Icelandic residents and residents. A advertising and marketing marketing campaign focusing on home vacationers was rolled out within the late spring; a global model can be unveiled as quickly as journey restrictions are lifted.

The voucher marketing campaign helped to jump-start demand for motels, eating places and points of interest. To this point, Icelanders have used greater than $1.2 million value of their free journey vouchers, that are legitimate by means of the top of the 12 months.

The summer season was “fairly good, contemplating every thing,” mentioned Bjarnheidur Hallsdottir, the chairwoman of the board of the Icelandic Journey Trade Affiliation and the chief government of two tourism corporations. “After which instantly out of nowhere, the federal government determined to alter the foundations on the borders. Since then, everyone seems to be crying.”

Beneath the brand new guidelines, which took impact in August, arriving passengers could select both to submit to 2 screening checks for the virus, separated by 5 days’ self-quarantine, or to skip border screening and self-quarantine for 14 days after arrival.

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